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Two binding modes reveal flexibility in kinase/response regulator interactions in the bacterial chemotaxis pathway

The crystal structure at 2.0-Å resolution of the complex of the Escherichia coli chemotaxis response regulator CheY and the phosphoacceptor-binding domain (P2) of the kinase CheA is presented. The binding interface involves the fourth and fifth helices and fifth β-strand of CheY and both helices of...

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Detalhes bibliográficos
Main Authors: McEvoy, Megan M., Hausrath, Andrew C., Randolph, Gannon B., Remington, S. James, Dahlquist, Frederick W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22608/
https://ncbi.nlm.nih.gov/pubmed/9636149
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