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Motif-directed network component analysis for regulatory network inference

BACKGROUND: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data and ChIP-on-chip data are available. However, a NCA scheme is not applicable to many biological studies due to limited top...

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Autors principals: Wang, Chen, Xuan, Jianhua, Chen, Li, Zhao, Po, Wang, Yue, Clarke, Robert, Hoffman, Eric
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259422/
https://ncbi.nlm.nih.gov/pubmed/18315853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-S1-S21
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