Effects of KP-496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A(2) receptor, on airway obstruction in guinea pigs

BACKGROUND AND PURPOSE: KP-496 is a novel dual antagonist for cysteinyl leukotriene receptor 1 (CysLT(1)) and thromboxane A(2) (TXA(2)) receptor (TP). The aim of this study was to evaluate the pharmacological profile of inhaled KP-496 and its effects on airway obstruction. EXPERIMENTAL APPROACH: Ant...

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Detaylı Bibliyografya
Asıl Yazarlar: Ishimura, M, Suda, M, Morizumi, K, Kataoka, S, Maeda, T, Kurokawa, S, Hiyama, Y
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2007
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259206/
https://ncbi.nlm.nih.gov/pubmed/18037905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707602
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