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Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions

We have previously found that the borders of evolutionarily conserved chromosomal regions often coincide with tumor-associated deletion breakpoints within human 3p12-p22. Moreover, a detailed analysis of a frequently deleted region at 3p21.3 (CER1) showed associations between tumor breaks and gene d...

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Detalhes bibliográficos
Main Authors: Darai-Ramqvist, Eva, Sandlund, Agneta, Müller, Stefan, Klein, George, Imreh, Stefan, Kost-Alimova, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259101/
https://ncbi.nlm.nih.gov/pubmed/18230801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.7010208
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