The Ets transcription factor Elf5 specifies mammary alveolar cell fate

Hormonal cues regulate mammary development, but the consequent transcriptional changes and cell fate decisions are largely undefined. We show that knockout of the prolactin-regulated Ets transcription factor Elf5 prevented formation of the secretory epithelium during pregnancy. Conversely, overexpre...

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Hauptverfasser: Oakes, Samantha R., Naylor, Matthew J., Asselin-Labat, Marie-Liesse, Blazek, Katrina D., Gardiner-Garden, Margaret, Hilton, Heidi N., Kazlauskas, Michael, Pritchard, Melanie A., Chodosh, Lewis A., Pfeffer, Peter L., Lindeman, Geoffrey J., Visvader, Jane E., Ormandy, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Research Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259028/
https://ncbi.nlm.nih.gov/pubmed/18316476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1614608
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