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Ex Vivo-Generated CD36(+) Erythroid Progenitors Are Highly Permissive to Human Parvovirus B19 Replication

The pathogenic parvovirus B19 (B19V) has an extreme tropism for human erythroid progenitor cells. In vitro, only a few erythroid leukemic cell lines (JK-1 and KU812Ep6) or megakaryoblastoid cell lines (UT7/Epo and UT7/Epo-S1) with erythroid characteristics support B19V replication, but these cells a...

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Main Authors: Wong, Susan, Zhi, Ning, Filippone, Claudia, Keyvanfar, Keyvan, Kajigaya, Sachiko, Brown, Kevin E., Young, Neal S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258946/
https://ncbi.nlm.nih.gov/pubmed/18160440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02247-07
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