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Human Immunodeficiency Virus Type 1 Vpr Inhibits Axonal Outgrowth through Induction of Mitochondrial Dysfunction

Human immunodeficiency virus type 1 (HIV-1)-infected macrophages damage mature neurons in the brain, although their effect on neuronal development has not been clarified. In this study, we show that HIV-1-infected macrophages produce factors that impair the development of neuronal precursor cells an...

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Detalhes bibliográficos
Main Authors: Kitayama, Hiroko, Miura, Yoshiharu, Ando, Yoshinori, Hoshino, Shigeki, Ishizaka, Yukihito, Koyanagi, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258941/
https://ncbi.nlm.nih.gov/pubmed/18094160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02094-07
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