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Direct Correlation between Sialic Acid Binding and Infection of Cells by Two Human Polyomaviruses (JC Virus and BK Virus)

For the human polyomaviruses JC virus (JCV) and BK virus (BKV), the first step to a successful infection involves binding to sialic acid moieties located on the surfaces of host cells. By stripping and then reconstituting specific sialic acid linkages on host cells, we show that JCV uses both α(2,3)...

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Detalles Bibliográficos
Main Authors: Dugan, Aisling S., Gasparovic, Megan L., Atwood, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258902/
https://ncbi.nlm.nih.gov/pubmed/18094176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02123-07
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