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Role and Regulation of Iron-Sulfur Cluster Biosynthesis Genes in Shigella flexneri Virulence

Shigella flexneri, a causative agent of bacterial dysentery, possesses two predicted iron-sulfur cluster biosynthesis systems called Suf and Isc. S. flexneri strains containing deletion mutations in the entire suf operon (UR011) or the iscSUA genes (UR022) were constructed. Both mutants were defecti...

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Detalhes bibliográficos
Main Authors: Runyen-Janecky, Laura, Daugherty, Aaron, Lloyd, Benjamin, Wellington, Christopher, Eskandarian, Haig, Sagransky, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258810/
https://ncbi.nlm.nih.gov/pubmed/18195027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01211-07
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