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The Hek Outer Membrane Protein of Escherichia coli Strain RS218 Binds to Proteoglycan and Utilizes a Single Extracellular Loop for Adherence, Invasion, and Autoaggregation

Escherichia coli is the principal gram-negative causative agent of sepsis and meningitis in neonates. The pathogenesis of meningitis due to E. coli K1 involves mucosal colonization, transcytosis of epithelial cells, survival in the bloodstream, and eventually invasion of the meninges. The last two a...

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Detalhes bibliográficos
Main Authors: Fagan, Robert P., Lambert, Matthew A., Smith, Stephen G. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258800/
https://ncbi.nlm.nih.gov/pubmed/18160475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01327-07
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