Comparative Efficacies of Rifaximin and Vancomycin for Treatment of Clostridium difficile-Associated Diarrhea and Prevention of Disease Recurrence in Hamsters

Clostridium difficile-associated colitis is an increasing cause of morbidity and mortality in hospitalized patients, with high relapse rates following conventional therapy. We sought to determine the efficacy of rifaximin, a novel nonabsorbed antibiotic, in the hamster model of C. difficile-associat...

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Bibliographic Details
Main Authors: Kokkotou, Efi, Moss, Alan C., Michos, Athanasios, Espinoza, Daniel, Cloud, Jeffrey W., Mustafa, Nasima, O'Brien, Michael, Pothoulakis, Charalabos, Kelly, Ciarán P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258528/
https://ncbi.nlm.nih.gov/pubmed/18195066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01143-07
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