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MUC1 Mucin Is a Negative Regulator of Toll-Like Receptor Signaling

MUC1 (MUC1 in humans and Muc1 in nonhuman species) is a transmembrane mucin-like glycoprotein expressed in epithelial cells lining various mucosal surfaces as well as hematopoietic cells. Recently, we showed that Muc1(−/−) mice exhibited greater inflammatory responses to Pseudomonas aeruginosa or it...

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Detalhes bibliográficos
Main Authors: Ueno, Keiko, Koga, Takeshi, Kato, Kosuke, Golenbock, Douglas T., Gendler, Sandra J., Kai, Hirofumi, Kim, K. Chul
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258447/
https://ncbi.nlm.nih.gov/pubmed/18079492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0336RC
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