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Expression of Human nPTB Is Limited by Extreme Suboptimal Codon Content
BACKGROUND: The frequency of synonymous codon usage varies widely between organisms. Suboptimal codon content limits expression of viral, experimental or therapeutic heterologous proteins due to limiting cognate tRNAs. Codon content is therefore often adjusted to match codon bias of the host organis...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2258417/ https://ncbi.nlm.nih.gov/pubmed/18335065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001801 |
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