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Platelet Binding and Biodistribution of (99m)Tc-rBitistatin in Animal Species and Humans

INTRODUCTION: (99m)Tc-rBitistatin is a radioligand for the αIIbβ3 (GPIIb/IIIa) receptor on platelets and is being developed as a diagnostic radiopharmaceutical for in vivo imaging of acute thrombi and emboli. Prior to the first administration of (99m)Tc-rBitistatin to human subjects, its biodistribu...

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Detalhes bibliográficos
Main Authors: Knight, Linda C., Romano, Jan E., Bright, Lewis T., Agelan, Alexis, Kantor, Steven, Maurer, Alan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258228/
https://ncbi.nlm.nih.gov/pubmed/17921036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2007.03.014
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