Pvt1-encoded microRNAs in oncogenesis

BACKGROUND: The functional significance of the Pvt1 locus in the oncogenesis of Burkitt's lymphoma and plasmacytomas has remained a puzzle. In these tumors, Pvt1 is the site of reciprocal translocations to immunoglobulin loci. Although the locus encodes a number of alternative transcripts, no p...

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Bibliografiske detaljer
Main Authors: Beck-Engeser, Gabriele B, Lum, Amy M, Huppi, Konrad, Caplen, Natasha J, Wang, Bruce B, Wabl, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2257975/
https://ncbi.nlm.nih.gov/pubmed/18194563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-4
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