Substrate specificity of new methyl-directed DNA endonuclease GlaI

BACKGROUND: Recently, we have discovered site-specific endonucleases, which recognize and cleave only DNA sequences with 5-methylcytosine. Two specificities of such endonucleases have been described. Enzymes BisI, BlsI, and GluI are isoschizomers and hydrolyze the DNA sequence 5'-GCNGC-3'/...

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Bibliografiske detaljer
Main Authors: Tarasova, Galina V, Nayakshina, Tatiana N, Degtyarev, Sergey KH
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2257971/
https://ncbi.nlm.nih.gov/pubmed/18194583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-7
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