Recombinant human erythropoietin increases survival and reduces neuronal apoptosis in a murine model of cerebral malaria

BACKGROUND: Cerebral malaria (CM) is an acute encephalopathy with increased pro-inflammatory cytokines, sequestration of parasitized erythrocytes and localized ischaemia. In children CM induces cognitive impairment in about 10% of the survivors. Erythropoietin (Epo) has – besides of its well known h...

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Detalhes bibliográficos
Main Authors: Wiese, Lothar, Hempel, Casper, Penkowa, Milena, Kirkby, Nikolai, Kurtzhals, Jørgen AL
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2257967/
https://ncbi.nlm.nih.gov/pubmed/18179698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-3
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