Virulence factor rtx in Legionella pneumophila, evidence suggesting it is a modular multifunctional protein

BACKGROUND: The repeats in toxin (Rtx) are an important pathogenicity factor involved in host cells invasion of Legionella pneumophila and other pathogenic bacteria. Its role in escaping the host immune system and cytotoxic activity is well known. Its repeated motives and modularity make Rtx a multi...

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Bibliographic Details
Main Authors: D'Auria, Giuseppe, Jiménez, Núria, Peris-Bondia, Francesc, Pelaz, Carmen, Latorre, Amparo, Moya, Andrés
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2257941/
https://ncbi.nlm.nih.gov/pubmed/18194518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-14
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