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Binding and Clustering of Glycosaminoglycans: A Common Property of Mono- and Multivalent Cell-Penetrating Compounds
Recent observations in cell culture provide evidence that negatively charged glycosaminoglycans (GAGs) at the surface of biological cells bind cationic cell-penetrating compounds (CPCs) and cluster during CPC binding, thereby contributing to their endocytotic uptake. The GAG binding and clustering o...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Biophysical Society
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2257919/ https://ncbi.nlm.nih.gov/pubmed/18065465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.113472 |
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