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Binding and Clustering of Glycosaminoglycans: A Common Property of Mono- and Multivalent Cell-Penetrating Compounds

Recent observations in cell culture provide evidence that negatively charged glycosaminoglycans (GAGs) at the surface of biological cells bind cationic cell-penetrating compounds (CPCs) and cluster during CPC binding, thereby contributing to their endocytotic uptake. The GAG binding and clustering o...

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Detalhes bibliográficos
Main Authors: Ziegler, André, Seelig, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2257919/
https://ncbi.nlm.nih.gov/pubmed/18065465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.113472
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