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The effect of actin disrupting agents on contact guidance of human embryonic stem cells

Mammalian cells respond to their substrates by complex changes in gene expression profiles, morphology, proliferation and migration. We report that substrate nanotopography alters morpohology and proliferation of human embryonic stem cells (hESCs). Fibronectin-coated poly(di-methyl siloxane) substra...

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Detalhes bibliográficos
Main Authors: Gerecht, Sharon, Bettinger, Christopher J., Zhang, Zhitong, Borenstein, Jeffrey, Vunjak-Novakovic, Gordana, Langer, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2257875/
https://ncbi.nlm.nih.gov/pubmed/17576011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2007.05.027
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