Several regions in the major histocompatibility complex confer risk for anti-CCP- antibody positive rheumatoid arthritis, independent of the DRB1 locus

Recent evidence suggests that additional risk loci for RA) are present in the major histocompatibility complex (MHC), independent of the class II HLA-DRB1 locus. We have now tested a total of 1769 SNPs across 7.5Mb of the MHC locating from 6p22.2 (26.03 Mb) to 6p21.32 (33.59 Mb) derived from the Ill...

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Detalhes bibliográficos
Main Authors: Lee, Hye-Soon, Lee, Annette T., Criswell, Lindsey A., Seldin, Michael F., Amos, Christopher I, Carulli, John P, Navarrete, Cristina, Remmers, Elaine F, Kastner, Daniel L., Plenge, Robert M, Li, Wentian, Gregersen, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2255558/
https://ncbi.nlm.nih.gov/pubmed/18309376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2007-00123.Lee
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