Several regions in the major histocompatibility complex confer risk for anti-CCP- antibody positive rheumatoid arthritis, independent of the DRB1 locus

Recent evidence suggests that additional risk loci for RA) are present in the major histocompatibility complex (MHC), independent of the class II HLA-DRB1 locus. We have now tested a total of 1769 SNPs across 7.5Mb of the MHC locating from 6p22.2 (26.03 Mb) to 6p21.32 (33.59 Mb) derived from the Ill...

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Détails bibliographiques
Auteurs principaux: Lee, Hye-Soon, Lee, Annette T., Criswell, Lindsey A., Seldin, Michael F., Amos, Christopher I, Carulli, John P, Navarrete, Cristina, Remmers, Elaine F, Kastner, Daniel L., Plenge, Robert M, Li, Wentian, Gregersen, Peter K.
Format: Artigo
Langue:Inglês
Publié: ScholarOne 2008
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2255558/
https://ncbi.nlm.nih.gov/pubmed/18309376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2007-00123.Lee
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