Prevention of acute graft-versus-host disease by blocking T-cell entry to secondary lymphoid organs

In acute graft-versus-host disease (aGVHD), donor T cells attack the recipient's gastrointestinal tract, liver, and skin. We hypothesized that blocking access to distinct lymphoid priming sites may alter the specific organ tropism and prevent aGVHD development. In support of this initial hypoth...

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Main Authors: Beilhack, Andreas, Schulz, Stephan, Baker, Jeanette, Beilhack, Georg F., Nishimura, Ryosei, Baker, Enosh M., Landan, Gilad, Herman, Edward I., Butcher, Eugene C., Contag, Christopher H., Negrin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2008
Assuntos:
Transplantation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254542/
https://ncbi.nlm.nih.gov/pubmed/17989315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-112789
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