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Bipolar localization of Bacillus subtilis topoisomerase IV, an enzyme required for chromosome segregation

In Bacillus subtilis, parE and parC were shown to be essential genes for the segregation of replicated chromosomes. Disruption of either one of these genes resulted in failure of the nucleoid to segregate. Purified ParE and ParC proteins reconstituted to form topoisomerase IV (topo IV), which was hi...

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Main Authors: Huang, Wai Mun, Libbey, Jane L., van der Hoeven, Petra, Yu, Shelly Xiaohong
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC22545/
https://ncbi.nlm.nih.gov/pubmed/9539793
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