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Importance of TP53 codon 72 and intron 3 duplication 16bp polymorphisms in prediction of susceptibility on breast cancer

BACKGROUND: TP53 is one of major tumour suppressor genes being essential in preservation of genome integrity. Two very common polymorphisms have been demonstrated to contribute to cancer susceptibility and tumour behaviour. The purpose of this study was to evaluate the role of Arg72Pro and PIN3 Ins1...

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Autors principals: Costa, Sandra, Pinto, Daniela, Pereira, Deolinda, Rodrigues, Helena, Cameselle-Teijeiro, Jorge, Medeiros, Rui, Schmitt, Fernando
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254432/
https://ncbi.nlm.nih.gov/pubmed/18230179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-32
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