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Distribution of Systemic Ciprofloxacin and Doxycycline to Gingiva and Gingival Crevicular Fluid

BACKGROUND: Systemic fluoroquinolones and tetracyclines reach steady-state levels in gingival crevicular fluid (GCF) that are several-fold higher than their levels in serum. The mechanism by which this occurs is unclear, but gingival fibroblasts are known to accumulate these agents. Uptake by fibrob...

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Bibliografiska uppgifter
Huvudupphovsmän: Lavda, Maria, Clausnitzer, C. Esther, Walters, John D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2004
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254337/
https://ncbi.nlm.nih.gov/pubmed/15732869
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