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Independent Introduction of Two Lactase-Persistence Alleles into Human Populations Reflects Different History of Adaptation to Milk Culture

The T(−13910) variant located in the enhancer element of the lactase (LCT) gene correlates perfectly with lactase persistence (LP) in Eurasian populations whereas the variant is almost nonexistent among Sub-Saharan African populations, showing high prevalence of LP. Here, we report identification of...

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Detalhes bibliográficos
Main Authors: Enattah, Nabil Sabri, Jensen, Tine G.K., Nielsen, Mette, Lewinski, Rikke, Kuokkanen, Mikko, Rasinpera, Heli, El-Shanti, Hatem, Seo, Jeong Kee, Alifrangis, Michael, Khalil, Insaf F., Natah, Abdrazak, Ali, Ahmed, Natah, Sirajedin, Comas, David, Mehdi, S. Qasim, Groop, Leif, Vestergaard, Else Marie, Imtiaz, Faiqa, Rashed, Mohamed S., Meyer, Brian, Troelsen, Jesper, Peltonen, Leena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Human Genetics 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253962/
https://ncbi.nlm.nih.gov/pubmed/18179885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2007.09.012
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