Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol

Scavenger receptor BI (SR-BI) is a cell surface receptor that binds high density lipoproteins (HDL) and mediates selective uptake of HDL cholesteryl esters (CE) in transfected cells. To address the physiological role of SR-BI in HDL cholesterol homeostasis, mice were generated bearing an SR-BI promo...

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Autori principali: Varban, Mariet Lee, Rinninger, Franz, Wang, Nan, Fairchild-Huntress, Victoria, Dunmore, Judy H., Fang, Qing, Gosselin, Michael L., Dixon, Kristen L., Deeds, James D., Acton, Susan L., Tall, Alan R., Huszar, Dennis
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC22539/
https://ncbi.nlm.nih.gov/pubmed/9539787
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