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Different mechanisms for suppression of apoptosis by cytokines and calcium mobilizing compounds

Overexpression of wild-type p53 in M1 myeloid leukemia cells induces apoptotic cell death that was suppressed by the calcium ionophore A23187 and the calcium ATPase inhibitor thapsigargin (TG). This suppression of apoptosis by A23187 or TG was associated with suppression of caspase activation but no...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lotem, Joseph, Sachs, Leo
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22536/
https://ncbi.nlm.nih.gov/pubmed/9539784
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