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Cryoelectron microscopy reveals new features in the three-dimensional structure of phosphorylase kinase
Phosphorylase kinase (PhK), a regulatory enzyme in the cascade activation of glycogenolysis, is a 1.3-MDa hexadecameric complex, (αβγδ)(4). PhK comprises two arched octameric (αβγδ)(2) lobes that are oriented back-to-back with overall D(2) symmetry and connected by small bridges. These interlobal br...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253458/ https://ncbi.nlm.nih.gov/pubmed/15741332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041123905 |
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