Loading...

Specificity and reactive loop length requirements for crmA inhibition of serine proteases

The viral serpin, crmA, is distinguished by its small size and ability to inhibit both serine and cysteine proteases utilizing a reactive loop shorter than most other serpins. Here, we characterize the mechanism of crmA inhibition of serine proteases and probe the reactive loop length requirements f...

Full description

Saved in:
Bibliographic Details
Main Authors: Tesch, Lisa D., Raghavendra, Manikanahally P., Bedsted-Faarvang, Tina, Gettins, Peter G.W., Olson, Steven T.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253425/
https://ncbi.nlm.nih.gov/pubmed/15632287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041104905
Tags: Add Tag
No Tags, Be the first to tag this record!