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The H2A.Z/H2B dimer is unstable compared to the dimer containing the major H2A isoform

The nucleosome, the basic fundamental repeating unit of chromatin, contains two H2A/H2B dimers and an H3/H4 tetramer. Modulation of the structure and dynamics of the nucleosome is an important regulation mechanism of DNA-based chemistries in the eukaryotic cell, such as transcription and replication...

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Detalles Bibliográficos
Autores principales: Placek, Brandon J., Harrison, L. Nicole, Villers, Brooke M., Gloss, Lisa M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253418/
https://ncbi.nlm.nih.gov/pubmed/15632282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041026405
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