Učitavanje...
Modifications of human βA1/βA3-crystallins include S-methylation, glutathiolation, and truncation
Disulfide bonding of lens crystallins contributes to the aggregation and insolubilization of these proteins that leads to cataract. A high concentration of reduced glutathione is believed to be key in preventing oxidation of crystallin sulfhydryls to form disulfide bonds. This protective role is dec...
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Glavni autori: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Cold Spring Harbor Laboratory Press
2005
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253330/ https://ncbi.nlm.nih.gov/pubmed/15576560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04738505 |
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