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Enzyme adaptation to alkaline pH: Atomic resolution (1.08 Å) structure of phosphoserine aminotransferase from Bacillus alcalophilus

The crystal structure of the vitamin B(6)-dependent enzyme phosphoserine aminotransferase from the obligatory alkaliphile Bacillus alcalophilus has been determined at 1.08 Å resolution. The model was refined to an R-factor of 11.7% (R(free) = 13.9%). The enzyme displays a narrow pH optimum of enzyma...

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Detalles Bibliográficos
Autores principales: Dubnovitsky, Anatoly P., Kapetaniou, Evangelia G., Papageorgiou, Anastassios C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253317/
https://ncbi.nlm.nih.gov/pubmed/15608117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041029805
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