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The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii

The S-adenosyl-L-methionine (SAM)-dependent methyltransferases represent a diverse and biologically important class of enzymes. These enzymes utilize the ubiquitous methyl donor SAM as a cofactor to methylate proteins, small molecules, lipids, and nucleic acids. Here we present the crystal structure...

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Autors principals: Sun, Warren, Xu, Xiaohui, Pavlova, Marina, Edwards, Aled M., Joachimiak, Andrzej, Savchenko, Alexei, Christendat, Dinesh
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253237/
https://ncbi.nlm.nih.gov/pubmed/16260766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051821805
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