Proopiomelanocortin (POMC), the ACTH/melanocortin precursor, is secreted by human epidermal keratinocytes and melanocytes and stimulates melanogenesis

Proopiomelanocortin (POMC) can be processed to ACTH and melanocortin peptides. However, processing is incomplete in some tissues, leading to POMC precursor release from cells. This study examined POMC processing in human skin and the effect of POMC on the melanocortin-1 receptor (MC-1R) and melanocy...

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Main Authors: Rousseau, Karine, Kauser, Sobia, Pritchard, Lynn E., Warhurst, Anne, Oliver, Robert L., Slominski, Andrzej, Wei, Edward T., Thody, Anthony J., Tobin, Desmond J., White, Anne
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253185/
https://ncbi.nlm.nih.gov/pubmed/17317724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.06-7398com
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