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Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein

CREB, the cAMP response element binding protein, is a key transcriptional regulator of a large number of genes containing a CRE consensus sequence in their upstream regulatory regions. Mice with a hypomorphic allele of CREB that leads to a loss of the CREBα and Δ isoforms and to an overexpression of...

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Autori principali: Rudolph, Dorothea, Tafuri, Anna, Gass, Peter, Hämmerling, Günter J., Arnold, Bernd, Schütz, Günther
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC22515/
https://ncbi.nlm.nih.gov/pubmed/9539763
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