The SKHR Motif Is Required for Biological Function of the VirR Response Regulator from Clostridium perfringens

The response regulator VirR and its cognate sensor histidine kinase, VirS, are responsible for toxin gene regulation in the human pathogen Clostridium perfringens. The C-terminal domain of VirR (VirRc) contains the functional FxRxHrS motif, which is involved in DNA binding and is conserved in many r...

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Bibliographic Details
Main Authors: McGowan, Sheena, O'Connor, Jennifer R., Cheung, Jackie K., Rood, Julian I.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC225049/
https://ncbi.nlm.nih.gov/pubmed/14526034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.20.6205-6208.2003
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