Changes in the Concentrations of Guanosine 5′-Diphosphate 3′-Diphosphate and the Initiating Nucleoside Triphosphate Account for Inhibition of rRNA Transcription in Fructose-1,6-Diphosphate Aldolase (fda) Mutants

Early screens for conditional lethal mutations that affected rRNA expression in Escherichia coli identified temperature-sensitive fda mutants (fda encodes the glycolytic enzyme fructose-1,6-diphosphate aldolase). It was shown that these fda(Ts) mutants were severely impaired in rRNA synthesis upon s...

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Bibliographic Details
Main Authors: Schneider, David A., Gourse, Richard L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC225048/
https://ncbi.nlm.nih.gov/pubmed/14526031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.20.6192-6194.2003
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