Oral Vaccination of Mice with Adenoviral Vectors Is Not Impaired by Preexisting Immunity to the Vaccine Carrier

E1 deletion adenoviral vectors of the human serotype 5 (AdHu5) and the chimpanzee serotype 68 (AdC68) expressing the rabies virus glycoprotein (rab.gp) were tested for induction of transgene product-specific antibodies upon intranasal or oral immunization of newborn mice. Both vectors induced antibo...

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Main Authors: Xiang, Z. Q., Gao, G. P., Reyes-Sandoval, A., Li, Y., Wilson, J. M., Ertl, H. C. J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC224991/
https://ncbi.nlm.nih.gov/pubmed/14512528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.10780-10789.2003
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