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Cytopathic and Noncytopathic Interferon Responses in Cells Expressing Hepatitis C Virus Subgenomic Replicons

Hepatitis C virus (HCV) is the only known positive-stranded RNA virus that causes persistent lifelong infections in humans. Accumulation of HCV RNA can be inhibited with alpha interferon (IFN-α) in vivo and in culture cells. We used cell-based assay systems to investigate the mechanisms responsible...

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Autors principals: Guo, Ju-Tao, Zhu, Qing, Seeger, Christoph
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC224980/
https://ncbi.nlm.nih.gov/pubmed/14512527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.10769-10779.2003
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