Recovery of Infectious Foot-and-Mouth Disease Virus from Suckling Mice after Direct Inoculation with In Vitro-Transcribed RNA

We assayed the infectivity of naked foot-and-mouth disease virus (FMDV) RNA by direct inoculation of suckling mice. Our results demonstrate that transcripts generated from full-length cDNA clones were infectious, as was virion-extracted RNA. Interestingly, infectious virus could be recovered from a...

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Detalhes bibliográficos
Main Authors: Baranowski, Eric, Molina, Nicolás, Núñez, José Ignacio, Sobrino, Francisco, Sáiz, Margarita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224978/
https://ncbi.nlm.nih.gov/pubmed/14512578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.11290-11295.2003
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