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Role of the Mutation Q252R in Activating Membrane Fusion in the Murine Leukemia Virus Surface Envelope Protein

Entry of retroviruses into host cells requires the fusion between the viral and cellular membranes. It is unclear how receptor binding induces conformational changes within the surface envelope protein (SU) that activate the fusion machinery residing in the transmembrane envelope protein (TM). In th...

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Detalhes bibliográficos
Main Authors: Lu, Chi-Wei, Roth, Monica J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224972/
https://ncbi.nlm.nih.gov/pubmed/14512534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.10841-10849.2003
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