Recombinant Virus Vaccination against “Self” Antigens Using Anchor-fixed Immunogens

To study the induction of anti-“self” CD8(+) T-cell reactivity against the tumor antigen gp100, we used a mouse transgenic for a chimeric HLA-A*0201/H-2 K(b) molecule (A2/K(b)). We immunized the mice with a recombinant vaccinia virus encoding a form of gp100 that had been modified at position 210 (f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Irvine, Kari R., Parkhurst, Maria R., Shulman, Eliza P., Tupesis, Janis P., Custer, Mary, Touloukian, Christopher E., Robbins, Paul F., Yafal, Alicia Gómez, Greenhalgh, Patricia, Sutmuller, Roger P. M., Offringa, Rienk, Rosenberg, Steven A., Restifo, Nicholas P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1999
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249691/
https://ncbi.nlm.nih.gov/pubmed/10363968
Tagiau: Ychwanegu Tag
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