The Effect of Central Loops in miRNA:MRE Duplexes on the Efficiency of miRNA-Mediated Gene Regulation

MicroRNAs (miRNAs) guide posttranscriptional repression of mRNAs. Hundreds of miRNAs have been identified but the target identification of mammalian mRNAs is still a difficult task due to a poor understanding of the interaction between miRNAs and the miRNA recognizing element (MRE). In recent resear...

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Detalhes bibliográficos
Main Authors: Ye, Wenbin, Lv, Qing, Wong, Chung-Kwun Amy, Hu, Sean, Fu, Chao, Hua, Zhong, Cai, Guoping, Li, Guoxi, Yang, Burton B., Zhang, Yaou
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248708/
https://ncbi.nlm.nih.gov/pubmed/18320040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001719
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