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The Skeletal Response to Estrogen is Impaired in Female but not in Male Steroid Receptor Coactivator (SRC)-1 Knock Out Mice

Estrogen (E) is critical for the maintenance of bone mass in both female and male mice and steroid receptor coactivator (SRC)-1 has been shown to be important for mediating E effects on bone, at least in female mice. In the present study, we defined the skeletal phenotype of male SRC-1 knock out (KO...

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Hlavní autoři: Mödder, U. I., Sanyal, A., Xu, J., O’Malley, B. W., Spelsberg, T. C., Khosla, S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248556/
https://ncbi.nlm.nih.gov/pubmed/18055287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2007.10.017
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