Loss of Functional Beta(2)-Microglobulin in Metastatic Melanomas From Five Patients Receiving Immunotherapy

BACKGROUND: In a subset of patients with metastatic melanoma, T lymphocytes bearing the cell-surface marker CD8 (CD8(+) T cells) can cause the regression of even large tumors. These antitumor CD8(+) T cells recognize peptide antigens presented on the surface of tumor cells by major histocompatibilit...

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Main Authors: Restifo, Nicholas P., Marincola, Francesco M., Kawakami, Yutaka, Taubenberger, Jeff, Yannelli, John R., Rosenberg, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: 1996
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248456/
https://ncbi.nlm.nih.gov/pubmed/8537970
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