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Discovering early molecular determinants of leukemogenesis
Truncating mutations of the G-CSF receptor are found during disease course in nearly half of all patients with severe congenital neutropenia. In this issue of the JCI, Liu et al. demonstrate that these mutations confer a competitive clonal advantage upon HSCs in mice and that the advantage is condit...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2248429/ https://ncbi.nlm.nih.gov/pubmed/18292805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35109 |
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