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Clustering of Genetically Defined Allele Classes in the Caenorhabditis elegans DAF-2 Insulin/IGF-1 Receptor

The DAF-2 insulin/IGF-1 receptor regulates development, metabolism, and aging in the nematode Caenorhabditis elegans. However, complex differences among daf-2 alleles complicate analysis of this gene. We have employed epistasis analysis, transcript profile analysis, mutant sequence analysis, and hom...

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Main Authors: Patel, Dhaval S., Garza-Garcia, Acely, Nanji, Manoj, McElwee, Joshua J., Ackerman, Daniel, Driscoll, Paul C., Gems, David
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248335/
https://ncbi.nlm.nih.gov/pubmed/18245374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.070813
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