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A two-step process for thymic regulatory T cell development

Recognition of self-antigens is required for regulatory T (T(reg)) cells to exert dominant tolerance. However, the mechanism by which self-reactive developing T cells are diverted into the T(reg) cell subset is unclear. To address this question, we looked for the immediate precursors to T(reg) cells...

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Hlavní autoři: Lio, Chan-Wang Joaquim, Hsieh, Chyi-Song
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248212/
https://ncbi.nlm.nih.gov/pubmed/18199417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.11.021
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