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The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiae

Initiation factor eIF4G is an essential protein required for initiation of mRNA translation via the 5′ cap-dependent pathway. It interacts with eIF4E (the mRNA 5′ cap-binding protein) and serves as an anchor for the assembly of further initiation factors. With treatment of Saccharomyces cerevisiae w...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Berset, Catherine, Trachsel, Hans, Altmann, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1998
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22477/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539725/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4264
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